电生理学证据证明爬行动物心脏中的右心房心脏起器环
Valentina Prosheva1, Vladimir Vityazev2, Elena Lebedeva2
1Institute of Physiology, Кomi Science Centre, Ural Branch of the Russian Academy of Sciences, 50 Pervomayskaya Street, 167982, Syktyvkar, Russia. V.Prosheva@physiol.komisc.ru.
概括
爬行动物的心脏 爬行动物的心脏
科学领域:
- 心脏病学 心脏病学
- 比较生理学比较生理学
- 电子生理学 电子生理学
背景情况:
- 心脏起器心房 (AV) 环已知存在于哺乳动物和鸟类的心脏中.
- 对爬行动物的心脏起器存在有限的电生理学数据.
研究的目的:
- 为了描述普通心脏中的AV环.
- 为了研究爬行动物心脏起器细胞的电生理特性.
主要方法:
- 传统的微电极技术用于隔离的心脏制剂.
- 进行了鼻腔 (SA) 区域脱落,以揭示AV结节节律.
- 从AV环细胞记录了动作潜力 (AP).
主要成果:
- 在SA区域脱离时,AV交叉处的节律活动被揭露.
- 记录的APs表现出特征性的透析脱极化.
- 节拍细胞位于右侧AV的心房孔周围.
- 电生理学特性与哺乳动物和鸟类节拍器细胞有相似之处.
结论:
- 爬行动物心脏中的AV环表现出内在的节拍活动.
- 爬行动物AV环心脏起器细胞与哺乳动物和鸟类的电生理学相似之处很大.
- 这项研究提供了爬行动物AV环的第一个电生理学表征.
相关概念视频
The Cardiac Cycle
The heart beats rhythmically in a sequence called the cardiac cycle—a rapid coordination of contraction (systole) and relaxation (diastole).
The Process
Electrical signals—sent from the sinoatrial (SA) node in the right atrial wall to the atrioventricular (AV) node between the right atrium and right ventricle—cause both atria to simultaneously contract. When the signal reaches the AV node, it pauses for approximately a tenth of a second, allowing the atria to contract and empty blood into the...
The Process
Electrical signals—sent from the sinoatrial (SA) node in the right atrial wall to the atrioventricular (AV) node between the right atrium and right ventricle—cause both atria to simultaneously contract. When the signal reaches the AV node, it pauses for approximately a tenth of a second, allowing the atria to contract and empty blood into the...
Electrophysiology of Normal Cardiac Rhythm
The normal cardiac rhythm is a synchronized electrical activity that facilitates the regular and coordinated contraction of the heart muscle. This process is essential for efficient blood circulation throughout the body. The fundamental elements involved in establishing and maintaining this rhythm include the unique electrical properties of cardiac muscle cells, the sinoatrial (SA) node's pacemaker function, the specialized conducting system, and the ionic mechanisms underlying each phase of...
Chambers of the Heart
The human heart is a complex organ made up of four chambers: the right and left atria and the right and left ventricles. These internal chambers are separated by partitions known as the interatrial and interventricular septa. The exterior of the heart features a groove known as the coronary sulcus that demarcates the atria from the ventricles, while the anterior and posterior interventricular sulci distinguish between the two ventricles.
Deoxygenated blood from the body is received in the right...
Deoxygenated blood from the body is received in the right...
Conduction System of the Heart
Autorhythmicity is a term that refers to the heart's inherent ability to generate electrical signals and instigate muscle contractions. This self-regulating conduction system within the heart consists of two key components: the pacemaker cells and specialized conducting cells.
The pacemaker cells are located in two primary nodes: the sinoatrial (SA) node and the atrioventricular (AV) node. The SA node pacemaker cells can autonomously depolarize, triggering an action potential that leads to the...
The pacemaker cells are located in two primary nodes: the sinoatrial (SA) node and the atrioventricular (AV) node. The SA node pacemaker cells can autonomously depolarize, triggering an action potential that leads to the...
Development of the Heart
The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart tube by...
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart tube by...
Conduction System of the Heart
The cardiac conduction system produces and transmits electrical impulses that prompt myocardial contraction, ensuring efficient heart function. This intricate system ensures that the heart beats in a coordinated and efficient manner, beginning with the atria and then the ventricles. The conduction system optimizes cardiac output by maintaining this precise sequence, which is crucial for adequate blood circulation.
This system relies on the unique properties of nodal and Purkinje cells:...
This system relies on the unique properties of nodal and Purkinje cells:...


