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选择和描述HCV抗E2 VH1-69抗体的广泛中和类别

Andreas Soerensen1, Filip Popovic1, Christina Holmboe Olesen1

  • 1Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Hvidovre and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark.

PLoS pathogens
|March 28, 2025
PubMed
概括

研究人员在C型肝炎病毒 (HCV) 包膜蛋白上发现了新的抗体标. 这些抗体表现出广泛的中和性,为开发有效的HCV疫苗提供了希望.

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Hepatitis01:25

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Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...