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通过临床试验化合物NITD-6888抑制登革热病毒的机制性见解

Yan Wang1, Long Sun1, Luciana Fernandes1

  • 1Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555.

Proceedings of the National Academy of Sciences of the United States of America
|March 28, 2025
PubMed
概括

登革热病毒 (DENV) 抑制剂NITD-688向非结构蛋白4B (NS4B),阻止必要的病毒复制复合体. 这种机制为登革热治疗提供了一个有前途的新战略.

关键词:
这就是DENV的意义.在 NITD-6888 中,在NS4B中,它是NS4B.这是一种抗病毒药物.弗拉维病毒 (flavivirus) 是一种病毒.

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