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Updated: May 11, 2026

Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in Pseudomonas aeruginosa
11:31

Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in Pseudomonas aeruginosa

Published on: June 30, 2016

通过准Pseudomonas aeruginosa中的PqsR来探索海洋天然产品作为潜在的定数感知抑制剂:虚拟查辅助结构动力学研究

Manikandan Jayaraman1, Vijayakumar Gosu2, Rajalakshmi Kumar3

  • 1Structural Biology and Bio-Computing Lab, Department of Bioinformatics, Science Block, Alagappa University, Karaikudi, Tamil Nadu, India.

PloS one
|March 28, 2025
PubMed
概括

研究人员通过向PqsR蛋白来确定海洋天然产品来对抗抗生素耐药的Pseudomonas aeruginosa. 这些化合物显示出开发新疗法对抗这种危险的病原体的希望.

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