周围假肢关节感染诊断标准报告和使用中的差异:范围审查和呼吁制定标准报告框架
Alexandra L Hohmann1, Cristian A DeSimone1, Natalie A Lowenstein1
1Rothman Orthopaedic Institute, Philadelphia, PA, USA.
Clinical orthopaedics and related research
|March 28, 2025
概括
许多周围假肢关节感染 (PJI) 研究缺乏方法透明度,经常出现引用错误和使用未经认可的标准. 建议采用标准化的报告框架,以提高PJI研究的有效性和可重复性.
科学领域:
- 整形外科手术 整形外科手术
- 传染性疾病 传染性疾病
- 医学研究方法学 医学研究方法学
背景情况:
- 周围假肢关节感染 (PJI) 存在许多基于标准的定义,但它们在研究中的使用和报告尚未被系统地评估.
- 评估PJI定义的应用对于确保研究有效性,可重复性和建立最佳实践至关重要.
- 缺乏标准化的报告阻碍了研究PJI的研究的比较和可靠性.
研究的目的:
- 对自2012年以来发表的定义PJI的研究进行范围审查.
- 为了确定哪些PJI定义最常被引用.
- 评估PJI研究方法中的定义标准,评分系统和与引用的来源对齐的报告.
主要方法:
- 在PubMed搜索中,在2012年1月至2023年8月期间发表的研究中,发现了75个独特的PJI定义引用.
- 分析了六个正式的PJI定义 (2011年MSIS,2013年MSIS/ICM,2013年IDSA,2018年ICM,2021年EBJIS以及一个未经批准的2018年定义).
- 评价了457项引用研究的引用准确性,报告定义细节和修改已发表的标准.
主要成果:
- 2011年的MSIS定义被引用最多 (40%),其次是2013年的MSIS/ICM (30%),尽管有更新的定义.
- 只有31%的研究详细介绍了PJI定义标准,不仅仅是引用,18%的研究修改了现有的定义.
- 显著的19%的研究表明,PJI定义和引用的来源之间存在差异,通常涉及未经批准的标准.
结论:
- 通常引用的PJI定义 (2011/2013 MSIS) 尽管存在较新的选择,但仍然存在,这表明采用可能存在滞后.
- 广泛缺乏方法透明度,引用错误和使用未经认可的标准是PJI研究中的系统问题.
- 迫切需要一个标准化的报告框架,以提高周围假肢关节感染研究的有效性和可重复性.
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