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Saif Zako¹, David Naguib¹, Kathrin Klein¹

¹Department of Cardiology, Pulmonology, and Vascular Medicine, University Hospital Düsseldorf, Medical Faculty of the Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

The Journal of invasive cardiology

|March 28, 2025

概括

新的闭合方法,Z-和Perclose ProGlide,在穿皮专利孔圆关闭后,显示出与手动压缩用于静脉通道的安全性和有效性相比,出血事件的发生率也相似.

科学领域:

干预心脏病学干预心脏病学
血管接入管理系统

背景情况:

静脉接入对于干预性心脏病手术,如PFO关闭,至关重要.
手动压缩是传统的血液静止方法,但存在出血风险.
新的静脉关闭技术旨在提高安全性和有效性.

研究的目的:

为了比较Z,Perclose ProGlide和手动压缩用于静脉血静止的安全性和有效性.
为了评估经皮穿透专利孔圆形关闭后的出血并发症.

主要方法:

一个单一中心的观察性研究包括220名接受PFO关闭的患者.
患者被准随机分为Z,Perclose ProGlide或手动压缩.
出血事件使用出血学术研究联盟 (BARC) 的分类来评估.

主要成果:

两组之间没有观察到BARC出血事件 (≥2) 的显著差异 (14.2%的手动压缩,14.5%的Z,15%的ProGlide;P = .9).
在手动压缩组中发生了一次严重出血事件 (BARC 3).
在所有组中都没有报告BARC 4或5出血事件.

结论:

Z-suture和Perclose ProGlide是手动压缩的安全有效替代品,用于PFO关闭后的静脉封闭.
这些接介导的技术提供可比的血液静止与类似的低出血率.

关键词:

关闭PFO的关闭访问站点管理,出血血液静止血液静止血液静止专利的形圆形孔.

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