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从1995年到2023年脊柱肌肉缩的研究趋势:一个文献计量分析

Hao Yu¹, Cuijie Wei², Dan Sun³

¹Department of Medical Genetics and Center for Rare Diseases, Second Affiliated Hospital, Zhejiang University School of Medicine and Zhejiang Key Laboratory of Rare Diseases for Precision Medicine and Clinical Translation, Hangzhou, China.

|March 28, 2025

概括

全球脊柱肌缩 (SMA) 研究显示显著增长,特别是在基因疗法和分子机制方面. 中国中国中国中国.

科学领域:

神经学神经学
遗传学是一个遗传学.
生物医学研究生物医学研究

背景情况:

脊髓肌肉缩 (SMA) 是一种进展性神经肌肉疾病,导致运动神经元退化.
对生存运动神经元1 (SMN1) 基因的发现推动了主要的治疗进展.
全球对SMA及其治疗方法的研究趋势需要全面分析.

研究的目的:

对脊髓肌肉缩 (SMA) 研究和治疗的全球趋势进行文献分析.
具体研究中国对SMA研究日益增长的贡献.

主要方法:

一项系统的搜索从1995年到2023年确定了4506份出版物.
图书统计工具被用来分析出版成果,合作和研究主题.

主要成果:

全球SMA研究已大幅扩大,以美国,英国和德国为首.
中国对SMA研究的参与正在增加,在基因疗法和分子机制等关键领域做出了显著贡献.
中国研究人员显示,关于SMA相关主题的报道频率很高.

结论:

图书统计分析揭示了全球SMA研究的实质性进展和未来方向.
这些发现为中国的研究人员,临床医生和政策制定者提供了洞察力,使其与国际进展保持一致.
该研究旨在改善受 SMA 影响的个体的治疗结果.

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