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使用白色生物技术工具包编辑天然纯素,通过mTOR途径研究它们的抗癌活性

Ahmed M Younis1, Ghada Attia1, Mohamed M Saleh2

  • 1Department of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt.

Bioorganic chemistry
|March 28, 2025
PubMed
概括

微生物对纯素类化合物的转化产生了9种代谢物. 化合物M9通过抑制mTOR显示出对癌细胞的显著细胞毒性潜力,提供了安全的,自然衍生的治疗选择.

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