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Updated: May 3, 2026

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利用现实世界的数据来推进生物标志物发现和精确瘤学的研究

Jiaqian Luo1, David B Solit2

  • 1Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; BCMB Allied Program, Graduate School of Medical Sciences, Weill Cornell Medicine, New York, NY, USA.

Cancer cell
|March 28, 2025
PubMed
概括

精确瘤学依赖于生物标志物,但面临诸如耐药性等挑战. 现实数据和特殊响应者的分析可以识别新的生物标志物并改善癌症治疗策略.

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
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