门内镜性肌肉切除术用于症状性吹出肌肉切除术,这是因为先前的肌肉切除术导致了秋症
Zhao-Chao Zhang1,2, Jia-Qi Xu1,2, Hai-Ting Pan1,2
1Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Endoscopy
|March 28, 2025
概括
救援口腔内镜性肌肉切除术 (POEM) 是一种安全有效的治疗方法,用于经历爆发性肌肉切除术 (BOM) 后出现复发性秋拉症症状的患者. 这种内镜手术在没有先前BOM的患者中提供了与POEM相比的临床成功率.
科学领域:
- 胃肠病学 胃肠病学
- 最少侵入性的手术
- 内镜检查是指内镜检查.
背景情况:
- 吹出肌肉切除术 (BOM) 可能导致由于食道排空受损而导致持久或反复出现的阿喀拉西亚症状.
- 对于那些对初始治疗没有反应的具有症状的BOM患者,需要进行救援程序.
研究的目的:
- 为了评估救援口腔内镜肌肉切除术 (POEM) 的安全性和有效性,在先前吹出肌肉切除术 (BOM) 后出现症状复发的秋拉西亚患者中.
主要方法:
- 一项回顾性研究比较了77名具有症状BOM的患者和168名没有BOM的患者,他们接受了救援POEM.
- 对操作相关参数,不良事件和临床成功率在2年随访后的分析.
主要成果:
- 对症状性BOM的救援POEM的平均手术持续时间为60.8分钟,平均住院时间为3.2天.
- 不良事件,包括粘膜损伤和与气体有关的并发症,在有和没有BOM的患者之间是可比的.
- 随访2年后的临床成功率在两组之间是相似的 (85.7%的BOM与92.3%的非BOM,P = 0.16).
结论:
- 口腔内镜性肌肉切除术 (POEM) 是一种可行且有效的治疗选择,用于症状爆发性肌肉切除术 (BOM) 的患者.
- 拯救POEM在没有BOM病史的患者中显示出与POEM相比的安全性和有效性.
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