相关实验视频

Updated: May 5, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

异形细粒状轨道炎症:病例系列和文献综述

Sonia Huang¹, Valerie Juniat², Jessica Y Tong¹

¹The University of Adelaide, Adelaide, South Australia, Australia; Royal Adelaide Hospital and South Australian Institute of Ophthalmology, Adelaide, South Australia, Australia.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie

|March 28, 2025

概括

异形细粒状轨道炎症通常在老年人中单方面呈现. 这项研究突出了关键的临床和放射性特征,以帮助区分它与其他导致颗粒状炎症的原因.

科学领域:

眼科医生眼科眼科
病理学病理学病理学
放射学放射学是指放射学

背景情况:

异常性颗粒状轨道炎症 (IGOI) 定义不完善,原因是与其他颗粒状状况重叠,特别是轨道沙科毒性.
将IGOI与其他原因区分开来是具有挑战性的,但对于适当的管理至关重要.

研究的目的:

为了确定与原发性粒状轨道炎症不同于其他粒状炎症原因的临床放射学特征.
通过一系列案例和文献综述,增强对IGOI的理解.

主要方法:

回顾12名被诊断患有IGOI的患者的病例系列.
关于粒状轨道炎症的现有医学文献的全面审查.

主要成果:

该研究包括12名患者,其中66.7%为女性,平均年龄为57.8岁.
常见的症状包括可触摸的质量 (83.3%),眼胀 (75%),眼外运动减少 (33.3%) 和亡 (33.3%).
大多数病例是单边的 (91.7%),50%的患者患有眼腺干扰. 治疗包括免疫抑制剂 (66.7%) 或手术 (16.7%).

结论:

与轨道沙科毒症相比,异形粒状轨道炎症通常单方面呈现,并且在较晚的年龄出现.
虽然差异化仍然很困难,但所识别的特征有助于更好地了解IGOI.
在63.6%的患者中观察到完全康复,41.7%的患者在随访时表现出稳定的疾病.

更多相关视频

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Published on: August 4, 2022

相关概念视频

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Microbiome of the Eye

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...

Chronic Inflammation: Introduction

Chronic Inflammation: Introduction

Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...