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Updated: May 5, 2026

A Multiplexed Luciferase-based Screening Platform for Interrogating Cancer-associated Signal Transduction in Cultured Cells
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通过激活HIF1通路,FSTL3促进结直肠癌的发生

Xiang-Rong Luo1, Li-Zhe Huang2, Jie Yin3

  • 1Department of Colorectal & Anal Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region 530021, PR China; The Central Hospital of Shaoyang, No. 36, Hongqi Road, Shaoyang City, Hunan Province 422000, PR China.

Gene
|March 28, 2025
PubMed
概括

富利斯塔丁类3 (FSTL3) 通过激活缺氧诱导因子1α (HIF1α) 途径促进结肠直肠癌 (CRC) 的生长和扩散. 用KC7F2抑制HIF1α可以逆转这些效应,这表明FSTL3是CRC的治疗点.

关键词:
生物标志物生物标志物结肠直肠癌是一种癌症.在FSTL3中使用.通过HIF1路径.瘤发生的发生因子.预测 预后 预测 预测

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