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Updated: Jul 15, 2026

Biochemical and Structural Characterization of the Carbohydrate Transport Substrate-binding-protein SP0092
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Published on: October 2, 2017

建立一种高效的基于结构的蛋白质聚类策略,以发现具有尚未探索的结构特征的银河糖4-O-硫转移酶

Wencui Chen1, Xiaohua Liu1, Zhi Zheng2

  • 1Fang Zongxi Center, MoE Key Laboratory of Marine Genetics and Breeding, College of Marine Life Sciences, Ocean University of China, Qingdao 266003, China; Laboratory for Marine Biology and Biotechnology, Qingdao Marine Science and Technology Center, Qingdao, China.

International journal of biological macromolecules
|March 28, 2025
PubMed
概括

研究人员首次确定了微生物银河糖4-O-硫转移酶 (G4STs). 这一发现为挖掘G4ST提供了新的方法,并扩大了它们在合成新型硫酸糖的用途.

关键词:
碳水化合物硫酸转移酶的作用催化机制是一种催化机制.银河糖4-O-硫酸转移酶 (G4ST) 是一种基于结构的蛋白质聚类.硫酸多糖化合物 硫酸多糖化合物硫化修饰的修饰方法

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Oligosaccharide Assembly01:24

Oligosaccharide Assembly

Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
Multiple sugar molecules that may or may...