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Updated: May 11, 2026

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
09:34

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在实验室中对SLCO2B1遗传变异的鉴定

Alli Sinokki1, Annika Miinalainen1, Saara Kivioja1

  • 1Drug Research Program, Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki FI-00014, Finland.

Journal of pharmaceutical sciences
|March 28, 2025
PubMed
概括

在OATP2B1载体 (编码SLCO2B1) 的遗传变异可以影响药物代谢. 罕见的变异c.1559G>C显著损害OATP2B1功能,影响药物处置.

关键词:
毒品运输是毒品的运输.遗传的多态性 (s)肝脏运输 肝脏运输肠道运输器 (s)膜输送器 (membrane transporter) 是一种用于输送膜的设备.有机阴离子载体多 (OATP)药物遗传学 药物遗传学单核酸多态 (单核酸多态,简称SNP)溶性载体 (SLC) 运输商 (SLC) 的运输商 (SLC) 的运输商 (SLC) 的运输商

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