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在血友病中增强血液静止功效,使用小的干扰性核糖核酸向蛋白质S

Raja Prince Eladnani1, Ute Schaeper2, Rim Diab1

  • 1Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; Department for BioMedical Research, University of Bern, Bern, Switzerland.

Journal of thrombosis and haemostasis : JTH
|March 28, 2025
PubMed
概括

抑制蛋白S (PS) 增加了血友血中的血栓生成. 一种新的PS小干扰RNA (siRNA) 疗法在不增加凝血风险的情况下,在血友病模型中恢复血静的承诺.

关键词:
血友病A型 血友病A型 血友病A型血友病 B 型 血友病 B 型血液静止 血液静止 血静止蛋白质 S 蛋白质 S 是一种蛋白质.小小的干扰RNA可以干扰RNA.

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