微塑料减少了受精土壤中抗生素耐药基因的自然衰减
Jin-Tao Yang1, Yu Zhang1, Shi-Yu Xiong1
1State Key Laboratory for Animal Disease Control and Prevention, South China Agricultural University, Guangzhou, 510642, PR China; Guangdong Key Laboratory for Veterinary Pharmaceutics Development and Safety Evaluation, College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, PR China.
Environmental pollution (Barking, Essex : 1987)
|March 28, 2025
概括
受精土中的微塑料阻碍了抗生素耐药性基因 (ARG) 的自然减少,促进了危险病原体的传播. 可持续实践对于管理MP污染及其长期环境风险至关重要.
科学领域:
- 环境科学 环境科学
- 土壤科学 土壤科学
- 微生物学 微生物学
背景情况:
- 长期的农业用地和便造成了土壤中显著的微塑料污染 (MP).
- 人们担心国会议员对土壤健康和生态系统功能的影响.
- MPs对抗生素耐药性基因 (ARG) 和受精土壤中的微生物群落的影响仍然基本上是未知的.
研究的目的:
- 在受肥土壤中,在MP压力下的自然减排过程中调查ARG的趋势和驱动因素.
- 探索传统和可生物降解的MP对ARG扩散的影响.
- 了解微生物群落和移动遗传元素 (MGE) 在MP诱导的ARG变化中的作用.
主要方法:
- 利用土壤微观宇宙实验来模拟MP污染.
- 采用元基因组分析来全面探索ARG趋势和驱动因素.
- 研究了聚乙烯糖酸MPs (PBS-MPs) 对ARG减缓率和ARG组成的影响.
主要成果:
- 聚丁酸MPs (PBS-MPs) 降低了ARG的自然衰减率,并在受精土壤中增加了高风险的ARG.
- 微生物群落和MGEs被确定为MP对ARG减缓抑制作用的关键驱动因素.
- 病原性细菌 (例如,Escherichia,沙门氏菌,Klebsiella) 被确定为ARG,金属耐药基因 (MRG) 和MGE的宿主.
- MP压力改变了碳源分布,减少了微生物的多样性和稳定性,并促进了ARG宿主如Dyella spp.的殖民.
- 这导致了土壤中ARG扩散的长期高风险状态.
结论:
- 受精土中的微塑料污染对抗生素耐药性基因 (ARG) 的持续和传播构成重大风险.
- 肌肉病的压力可能导致长期受到高毒性和抗生素耐药性细菌的污染,例如大肠杆菌.
- 可持续的农业实践对于减轻PM污染及其相关的环境风险,包括ARG的扩散至关重要.
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