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Updated: Jun 12, 2026

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通过CXCR3对小分子识别的结构可视化,揭示了CXCR3-CXCR7系统中的双重激动性

Shirsha Saha1, Fumiya K Sano2, Saloni Sharma1

  • 1Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, Kanpur, India.

Nature communications
|March 29, 2025
PubMed
概括

结构洞察力揭示了化学因受体CXCR3和CXCR7如何实现信号偏差和双重激动. 对G蛋白结合受体 (GPCR) 机制的这种理解提供了潜在的治疗策略.

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