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在不同类型的非斯特鲁维特结石中发现了细菌印记的证据

Felix Grases^1,2, Antonia Costa-Bauzá^3,4, Francesca Julià^1,2

¹Renal Lithiasis and Pathological Calcification Group, Research Institute of Health Sciences (IUNICS), University of the Balearic Islands, Palma, 07122, Spain.

|March 29, 2025

概括

在缺少 struvite 的结石中发现了细菌印记,特别是在酸中. 控制尿液pH值对于防止细菌介导的结石形成至关重要.

科学领域:

腎臟病學 (nephrology) 是一種醫學.
微生物学微生物学
材料科学材料科学材料科学

背景情况:

最近的研究表明,apatite酸盐和混合酸盐/apatite酸盐结石中存在细菌印记.
这些石头与斯特鲁维特石不同,不含斯特鲁维特.

研究的目的:

调查结石中细菌印记的存在和特征.
为了确定细菌印记,石材成分和尿液pH之间的关联.

主要方法:

在一年内对来自844名患者的903个结石进行了横截面研究.
分析包括立体显微镜,扫描电子显微镜与X射线微分析,和里埃变换红外光谱学.
当检测到细菌印记时,进行了生化和细菌性尿液分析.

主要成果:

鉴定了8个带有细菌印记的结石,但没有发现 struvite.
所有八个石头都含有酸,其印记位于这个矩阵内.
构成各异,包括纯酸,混合酸/氧酸盐,和氧酸单酸盐石头与酸核心.

结论:

细菌印记存在于缺乏 struvite 的各种结石中,始终存在于氧亚帕基基质中.
尿液pH值高于6.0可促进阿帕酸盐的形成和细菌的生长.
控制尿液pH值对于防止细菌媒介结石的发展至关重要.

关键词:

细菌印记是一个细菌印记.非尿酶产生细菌的细菌.脏结石 (renal calculi) 是指脏中的结石.尿路感染尿路感染尿液尿液尿液

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