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牛的生殖性能与便细菌组之间的关系的因果估计
Yutaka Taguchi1, Haruki Yamano1, Yudai Inabu1
1Kuju Agricultural Research Center, Graduate School of Agriculture, Kyushu University, Taketa, Oita, 878-0201, Japan.
Animal microbiome
|March 29, 2025
概括
肉牛的肠道细菌组成可以预测生殖成功. 在150天的年龄确定了特定的细菌群和代谢途径,与人工授精 (AI) 的成功有关,为群体管理提供了洞察力.
科学领域:
- 动物科学动物科学
- 微生物学 微生物学
- 生殖生物学 生殖生物学
背景情况:
- 肠道微生物组显著影响宿主生理学,但其在牛生殖表现中的作用尚不清楚.
- 了解肠道细菌对生殖效率的影响对于肉牛生产至关重要.
研究的目的:
- 为了研究肠道细菌组与日本黑的生殖表现之间的关系.
- 为了确定与人工授精 (AI) 成功相关的特定便细菌模式.
主要方法:
- 从150岁和300岁的母牛身上收集了便样本.
- 使用机器学习算法 (LDA,关联分析,随机森林,XGBoost) 和因果推断 (DirectLiNGAM) 来分析细菌组数据.
- 根据怀孕所需的AI周期,公牛被分为高级和低级组.
主要成果:
- 需要更少AI周期的母牛 (高级组) 显示了Rikenellaceae RC9肠组和Christensenellaceae R-7组的丰富性增加.
- 150天后的Erysipelotrichaceae家族,Clostridium sensu stricto1和家族XIII的AD3011组与AI数量的增加有关.
- 在150天的年龄,肌素降解途径 (PWY-4722) 与更高的AI数相关.
结论:
- 在AI之前近六个月的便细菌模式可能预测牛的生殖表现.
- 这项研究为肠道微生物群在生殖效率中的作用提供了新的视角,并为肉牛管理策略提供了信息.
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