环境温度和类似流感的疾病与急性尾炎的关联:使用22年数据的生态研究
On Tai Ken Yu1, Xiaoting Jiang1, Conglu Li1
1Jockey Club School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.
BMC public health
|March 29, 2025
概括
高温增加急性尾炎的入院率,而流感感染显示出保护作用. 需要进一步的研究,以了解这些环境协会的预防策略.
科学领域:
- 环境流行病学环境流行病学
- 传染病流行病学 传染病流行病学
- 公共卫生 公共卫生
背景情况:
- 急性尾炎是一个重要的全球健康问题,原因不完全理解.
- 以前的研究将尾炎与环境温度和流感独立联系起来.
- 这项研究同时研究温度和流感对尾炎的影响,以解决混因素.
研究的目的:
- 量化环境温度,流感活动和急性尾炎入院之间的关联.
- 在统一的统计模型中研究这些关系.
- 为了告知急性尾炎的潜在预防策略.
主要方法:
- 使用了来自香港 (1998-2019) 的人口级数据.
- 分析了针对特定流感菌株 (A/H1N1,A/H3N2,B) 的每周急性尾炎入院人数与每周平均温度和类似流感的疾病阳性 (ILI+) 率的分析.
- 采用了具有分布式滞后非线性函数和准波松分布的通用添加模型,用于多变量分析,控制湿度,降雨量和空气污染.
主要成果:
- 在更高的环境温度和急性尾炎入院之间观察到显著的积极关联.
- 流感A/H1N1和A/H3N2活动与急性尾炎入院有显著的负相关性.
- 在B型流感活动和急性尾炎入院之间没有发现显著的关联.
结论:
- 升高的体温与急性尾炎入院的增加相关.
- 流感感染似乎与急性尾炎有着保护性的关联.
- 建议对这些环境暴露的机制进行进一步的研究,以制定预防措施.
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