性别和年龄特定的差异在并发症和发作性心力衰竭之间的关联中
Weida Qiu1, Anping Cai1, Shiping Wu1
1Department of Cardiology, Hypertension Research Laboratory, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, China.
QJM : monthly journal of the Association of Physicians
|March 29, 2025
概括
伴随性疾病增加了心力衰竭 (HF) 的风险,女性和年轻人中更强烈的关联. 了解这些特定于性别和年龄的差异对于有针对性的HF预防策略至关重要.
科学领域:
- 心脏病学 心脏病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 关于伴随性疾病和发生性心力衰竭 (HF) 之间的性别和年龄特定关联的证据有限.
- 了解这些差异对于制定有效的预防策略至关重要.
研究的目的:
- 评估性和年龄特定的并发症与事件HF的关联.
- 计算导致HF风险的并发性疾病的人口归因分数 (PAF),按性别和年龄分层.
主要方法:
- 一项前性队列研究,对102,278名没有流行HF的中国成年人进行了研究.
- 参与者按性别和年龄分层 (<60或≥60岁).
- 医院住院记录确定了HF发病率,平均随访时间为3.5年.
主要成果:
- 年龄较大 (≥60岁),男性性别,以及大多数并发症与HF风险增加有关.
- 与HF的并发症关联在女性和年轻成人 (<60岁) 中更为明显.
- 总的来说,并发症占HF可归因部分的47.1%,具有显著的性别和年龄特异性差异.
结论:
- 在中国成年人中,伴随性疾病和发生性HF之间的关联存在显著的性别和年龄特异性差异.
- 这些发现强调了需要针对性,性别和年龄特定的预防方法来减轻HF风险.
更多相关视频
相关概念视频
Pathophysiology of Heart Failure
4.8K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
4.8K
Heart Failure I: Introduction
1.7K
Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
1.7K
Heart Failure II: Pathophysiology
1.9K
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
1.9K
Heart Failure III: Clinical Manifestations
1.2K
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
1.2K
Heart Failure IV: Classification and Diagnostic Evaluation
1.0K
Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
1.0K
Heart Failure VII: Nursing Interventions
787
The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
787


