在患有单侧脑的儿童中,日常生活执行功能和双月表现
Alexandra Kalkantzi1,2, Lize Kleeren1,2,3, Dieter Baeyens2,4
1Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium.
Developmental medicine and child neurology
|March 29, 2025
概括
患有单侧脑 (CP) 的儿童经常具有较差的执行功能,特别是当自闭症谱系障碍 (ASD) 存在时. 手动能力影响抑制,执行功能缺陷与双手表现问题相关.
科学领域:
- 儿科神经学 儿科神经学
- 发展心理学 发展心理学
- 康复医学 康复医学 康复医学
背景情况:
- 单侧脑 (CP) 影响运动功能,并可能影响认知能力.
- 执行功能对于日常生活活动和目标导向行为至关重要.
- 对于有针对性的干预来说,了解执行职能和单方面CP的双月表现之间的相互作用是很重要的.
研究的目的:
- 为了调查日常生活中报告的单边CP的儿童的执行功能.
- 在这个人群中检查执行职能与双月表现之间的关系.
- 探索自闭症谱系障碍 (ASD) 和手动能力对执行职能的影响.
主要方法:
- 一项涉及46名单边CP儿童 (平均年龄~11岁) 的横截面研究.
- 执行职能使用执行职能行为评级清单 (BRIEF) 进行评估.
- 用辅助手评估 (AHA) 和儿童手动使用经验问卷 (CHEQ) 评估双手表现.
- 统计分析包括一个样本的z测试,回归分析和非参数相关性.
主要成果:
- 与正常人相比,单边CP的儿童通常表现出较差的执行功能 (p ≤0.024).
- 执行功能的差异主要与ASD并发症有关 (p ≤ 0.001).
- 手动能力显著影响抑制 (p = 0.042).
- 在BRIEF和CHEQ (rs = -0.50至 -0.29) 之间发现了显著的相关性,以及与AHA (rs = -0.35) 的BRIEF抑制.
结论:
- 执行功能困难在单边CP中很常见,通常与ASD相关.
- 手动能力是抑制相关挑战的关键因素.
- 执行功能受损似乎与双月表现下降有关.
- 建议进行进一步的研究,包括基于绩效的执行职能评估.
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