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在CBP/EP300降解器的最新进展

Leonardo Palaferri1, Iván Cheng-Sánchez2, Cristina Nevado3

  • 1University of Zurich, Department of Chemistry, CH-8057 Zurich, Switzerland. leonardo.palaferri@chem.uzh.ch.

Chimia
|March 29, 2025
PubMed
概括

有针对性的蛋白质降解 (TPD) 使用新型的PROTAC和MGD来消除蛋白质. 针对CBP/EP300的新降解剂通过破坏转录来显示出有前途的抗癌剂.

关键词:
美国中央银行 (CBP) 的CBP.降解器降解器降解器EP300 EP300 在线播放这就是PROTAC.

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