左心室心肌功能的预后影响,在接受手术的患者中,为原发性心肌吐进行手术
Takeru Nabeta1,2,3, Ferande Peters4, Hoi W Wu5
1Department of Cardiology, Leiden University Medical Centre, Leiden, The Netherlands. takerunabeta@gmail.com.
The international journal of cardiovascular imaging
|March 29, 2025
概括
在手术前左心室全局工作指数 (LVGWI) 损伤,在患有 mitra regurgitation (MR) 的患者中预测死亡率更高. 这种心声回声测量可以提供超越LV全球纵向菌株 (LVGLS) 的预后见解.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 心脏外科手术 心脏外科手术
背景情况:
- 左心室肌肉工作 (LVMW) 通过包括LV后负载来评估左心室 (LV) 功能.
- 主要额头吐 (MR) 是一种需要手术干预的病症.
研究的目的:
- 评估 LVMW 指数的预后能力,在患有重症初级MR的患者中进行米特拉手术.
- 为了确定LVMW是否提供了LV全球纵向菌株 (LVGLS) 等既定标志物之外的额外预后信息.
主要方法:
- 包括306名接受手术的严重原发性MR患者.
- 术前的胸前心电回声被用于评估LVMW指数,包括LV全球工作指数 (LVGWI).
- 对于所有原因的死亡率,患者的平均随访时间为5.0年.
主要成果:
- 42%的患者患有LVGWI受损 (≤1900 mmHg%).
- 损伤的LVGWI或LVGLS (≤20%) 与显著较低的存活率有关.
- 除了LVGLS之外,LVGWI提供了所有原因死亡率的额外预后信息,尽管AUC,C指数和NRI的改善并不显著.
结论:
- 在接受手术的重症初级MR患者中,手术前LVGWI受损与死亡风险增加有关.
- 在这个患者队列中,LVGWI可能会提供超越LVGLS的增量预后价值.
- 需要进一步的研究来验证LVGWI的预后效用.
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