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Updated: Aug 11, 2026

Aptamer-Based Target Detection Facilitated by a 3-Stage G-Quadruplex Isothermal Exponential Amplification Reaction
03:38

Aptamer-Based Target Detection Facilitated by a 3-Stage G-Quadruplex Isothermal Exponential Amplification Reaction

Published on: October 6, 2022

独立的G-四重复/血红蛋白DNA酶:一种优质的现成催化剂,用于in situ成像分析

Jia Li1, Lanxin Jiang1, Haiping Wu2

  • 1Department of Clinical Molecular Medical detection center, Laboratory medicine center, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P.R. China.

Nucleic acids research
|March 29, 2025
PubMed
概括

研究人员开发了一种新型,高度活跃的G4/hemin DNA酶,通过对其组件进行共价连接. 这种工程DNAzyme为敏感的疾病标志物成像提供了增强的催化效率,比如乳腺癌中的HER2.

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Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes

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