在孕妇中影响接受新生儿RSV免疫接种的因素:一种混合方法研究
Dominique Gagnon1, Charlotte Gubany2, Manale Ouakki1
1Direction des risques biologiques, Institut national de santé publique du Québec, 945 Av. Wolfe, Québec (Québec), G1V 5B3, Canada.
Vaccine
|March 29, 2025
概括
孕妇对婴儿新型呼吸道同胞病毒 (RSV) 免疫非常感兴趣. 接受的关键因素包括疫苗的安全性,有效性和医疗保健提供者的建议,这对于预防婴儿住院至关重要.
科学领域:
- 公共卫生 公共卫生
- 免疫学 免疫学 免疫学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
背景情况:
- 呼吸道同胞病毒 (RSV) 是加拿大婴儿呼吸道疾病和住院治疗的重要原因.
- 加拿大卫生部批准了两项新的预防措施:母体疫苗和婴儿单克隆抗体.
- 了解孕妇对这些新型RSV预防方法的看法至关重要.
研究的目的:
- 评估孕妇对RSV及其预防的知识,态度和意图.
- 探索对母体疫苗接种与婴儿单克隆抗体的决策因素和偏好.
- 为了确定新的RSV免疫产品的吸收障碍和促进者.
主要方法:
- 在加拿大北克进行的一项混合方法研究 (2023年10月至12月).
- 在线调查 (n=803) 评估RSV知识,态度和对免疫产品的意图.
- 定性访谈 (n=25) 探讨了预防RSV的决策因素和偏好.
主要成果:
- 对于RSV母体疫苗接种 (88.1%) 和婴儿单克隆抗体 (92%) 的高度意愿.
- 大多数人更喜欢母体接种疫苗 (69%) 而不是婴儿抗体.
- 关键的接受因素包括婴儿保护,产品安全,有效性和医疗保健提供者的建议;安全问题也被注意到.
结论:
- 孕妇对母体疫苗接种和婴儿单克隆抗体对RSV预防都表现出强烈兴趣.
- 医疗保健提供者的建议和关于安全性和有效性的明确信息对于成功实施至关重要.
- 弥合意图和行动之间的差距需要解决家长的担忧,并提供基于证据的指导.
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