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Updated: Jun 25, 2026

Experimental Human Pneumococcal Carriage
07:47

Experimental Human Pneumococcal Carriage

Published on: February 15, 2013

使用人类挑战模型 (CHIPS) 确定最低的青素度以预防因Streptococcus pyogenes引起的喉炎:一种随机,双盲,安慰剂控制的随机试验

Thel K Hla1, Joshua Osowicki2, Julie A Marsh3

  • 1Wesfarmers Centre for Vaccines and Infectious Diseases, Telethon Kids Institute, Nedlands, WA, Australia; Medical School, University of Western Australia, Crawley, WA, Australia; Department of Infectious Diseases, Fiona Stanley Hospital, WA, Australia.

The Lancet. Microbe
|March 29, 2025
PubMed
概括

预防Streptococcus pyogenes 喉炎需要至少8.1 ng/mL的青素血度. 这一发现有助于优化青素剂量,以预防风湿性心脏病.

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A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii

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