通过AMPK信号通路,TSH抑制骨质细胞分化

Wenwen Zhang1, Yu Chen1, Yan Wang1

  • 1Key Laboratory of Endocrine Glucose & Lipids Metabolism and Brain Aging, Ministry of Education, Department of Endocrinology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China; Shandong Key Laboratory of Endocrinology and Lipid Metabolism, Jinan, Shandong 250021, China; Shandong Institute of Endocrine and Metabolic Diseases, Jinan, Shandong 250021, China; "Chuangxin China" Innovation Base of stem cell and Gene Therapy for endocrine Metabolic diseases, China; Shandong Engineering Laboratory of Prevention and Control for Endocrine and Metabolic Diseases, Jinan, Shandong 250021, China.

Gene
|March 29, 2025
PubMed
概括

甲状腺刺激激素 (TSH) 通过激活AMPK通路来抑制骨质损失,从而防止骨质疏松症. 这一发现为治疗骨疾病提供了新的治疗点.

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