在先天性腹膜的未下降丸的危险因素:日本的一项多中心研究
Satoshi Umeda1, Noriaki Usui1, Kouji Nagata2
1Department of Pediatric Surgery, Osaka Women's and Children's Hospital, Izumi, Japan.
Journal of pediatric surgery
|March 29, 2025
概括
未下降的丸 (UDT) 发生在12.3%的先天性隔膜 (CDH) 的男孩中. 较大的隔膜缺陷,特别是C/D型,是这些患者UDT的独立风险因素.
科学领域:
- 儿科手术 儿科手术
- 新生儿科学 新生儿科学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 先天性腹膜 (CDH) 是一种复杂的疾病,影响胎儿发育.
- 未下降的丸 (UDT) 是患有CDH的男性婴儿中常见的相关异常.
- 了解CDH中UDT的发病率和风险因素对于临床管理至关重要.
研究的目的:
- 为了确定在被诊断为CDH的男性患者中UDT的发生率.
- 确定与该人群中UDT发展相关的临床风险因素.
- 探索UDT与CDH缺陷有关的横向性.
主要方法:
- 来自日本CDH研究组数据库 (2006-2021) 的男性CDH患者的回顾性分析.
- 评估UDT发病率和需要花花症的患者在至少一年的时间内进行跟踪.
- 用UDT和没有UDT的CDH患者之间的临床特征的比较,以确定风险因素.
主要成果:
- 在408名患有CDH的合格男孩中,有50人 (12.3%) 经历过UDT;41人 (10.2%) 需要进行花百科.
- 在24例中,UDT发生在CDH的同一侧,在6例中发生在反侧,在20例中发生在双边.
- 较低的出生体重,较低的阿普加尔评分,非隔离缺陷",肝脏"呈现,C / D类型缺陷和补丁关闭与UDT有关.
结论:
- 在患有CDH的男孩中,UDT的发病率和对兰花的要求显著增加.
- 在CDH患者中,UDT可能会与隔膜缺陷发生在同一侧的倾向.
- 较大的隔膜缺陷,特别是C/D类型,被确定为CDH中UDT的独立风险因素.
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