酵母多糖化水凝的形成,结构特征和低血糖活性在体外
Chengyun Gan1, Xiaoxue Yin1, Yixuan He1
1School of Food Science and Engineering, Wuhan Polytechnic University, Wuhan 430023, China.
International journal of biological macromolecules
|March 30, 2025
概括
研究人员使用环保溶剂开发了新的酵母多糖化水凝 (H-YPs). 这些H-YP由于其结构和低血糖特性,对健康食品应用有很大的希望.
科学领域:
- 生物材料科学 生物材料科学
- 食品科学 食品科学 食品科学
- 生物化学 生物化学
背景情况:
- 酵母多糖具有有益的特性,如抗氧化剂和增强免疫力的作用.
- 酵母多糖的有限溶解性阻碍了它们的实际应用.
- 开发新的输送系统对于利用酵母多糖的潜力至关重要.
研究的目的:
- 从原始酵母多糖 (C-YP) 开发创新的酵母多糖水凝 (H-YPs).
- 描述准备好的H-YPs的结构和机械性能.
- 评估H-YP的体外低血糖活性和安全性.
主要方法:
- 作为原材料,使用了原始酵母多糖化物 (C-YP).
- 14%重量%的NaOH水溶液作为水凝制备的环保溶剂.
- 评估了机械性能 (硬度,凝强度),水含量和非细胞毒性.
- 进行了体外测试,以评估对α-葡萄糖酶和α-氨基酶的抑制活性.
主要成果:
- 准备好的H-YP具有多孔的网络结构和高含水量.
- 酵母多糖度的增加导致硬度 (665.0 gf) 和凝强度 (155.0 g*cm) 的提高.
- H-YPs表现出非细胞毒性特征,维持细胞活力超过80%,以及对α-葡萄糖酶和α-氨基酶的显著抑制活性.
结论:
- 通过使用环保的NaOH溶液,成功开发了新型酵母多糖化水凝 (H-YPs).
- H-YPs具有有利的机械性能和良好的生物相容性.
- 观察到的低血糖活性表明H-YPs在健康食品产品开发中的潜在应用.
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