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Updated: Jul 9, 2026

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[p53免疫组织化学与质瘤中的TP53突变之间的相关性]

X F Lin1, C C Hu1, P L Wang1

  • 1Department of Pathology, the First Affiliated Hospital of Fujian Medical University; Department of Pathology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, China.

Zhonghua bing li xue za zhi = Chinese journal of pathology
|March 30, 2025
PubMed
概括

p53免疫组织化学准确地预测了扩散性质瘤中的TP53基因突变. 阳性细胞≥20%的门表明突变,而完全负的结果表明需要进一步的基因测序.

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Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...