在老年肝硬化患者中,日常体力活动和肌肉之间的关系-一项多中心研究
Atsushi Hiraoka1, Tadashi Namisaki2, Masato Nakai3
1Department of Gastroenterology, Ehime Prefectural Central Hospital, Japan.
Internal medicine (Tokyo, Japan)
|March 30, 2025
概括
肝硬化患者的日常活动水平较低. 这项研究发现,日常步行和肌肉之间没有直接联系,这凸显了对抗萨科佩尼亚的干预措施的必要性.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 老年学是一门学科.
- 物理疗法物理治疗
背景情况:
- 肉症和肌肉在慢性肝病 (CLD) 中很常见.
- 了解日常活动的作用对于治疗肝硬化患者这些并发症至关重要.
- 他们遵循了日本关于诊断肉类症的指南.
研究的目的:
- 评估日间活动水平,按所采取的步骤测量,在日本肝硬化 (LC) 患者.
- 探索每日步数和肌肉发生之间的关系.
- 调查活动水平,肉症和肝功能之间的关联.
主要方法:
- 五十名LC患者 (25名男性,Child-Pugh A/B) 参与了这项研究.
- 每天的步数被用计步器监测了六个月.
- 根据日本肝病学学会的指导方针诊断出肉;手握强度和ALBI等级进行了评估.
主要成果:
- 平均每日步数为3,881步,没有显著的季节性变化.
- 肌肉影响了66%,手握力减少了34%,肉症存在于23.9%.
- 在每天步行和肌肉或手握强度之间没有发现显著的相关性. 患者的ALBI等级较差 (≥2b).
结论:
- 肝硬化患者的日常活动水平较低.
- 虽然每天的步骤与肌肉没有相关性,但需要进行干预,以保持活动并防止肉症的进展.
- 进一步研究改善这一群体体身体活动的有效策略是有必要的.
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