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Updated: May 7, 2026

A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants
10:44

A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants

Published on: August 9, 2019

与衰老相关的异常血统可塑性唤起T细胞介导的瘤控制

Dimitri Belenki1,2, Paulina Richter-Pechanska1, Zhiting Shao1

  • 1Charité - Universitätsmedizin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Hematology, Oncology and Tumor Immunology, and Molekulares Krebsforschungszentrum - MKFZ, Campus Virchow Klinikum, Berlin, Germany.

Nature communications
|March 30, 2025
PubMed
概括

在B细胞淋巴瘤中,细胞衰老触发了髓状细胞的可塑性,增强了T细胞的杀死,提高了生存率. 这种依赖衰老的可塑性为淋巴瘤治疗提供了有前途的治疗点.

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