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Updated: May 11, 2026

Measuring the Mechanical Properties of Living Cells Using Atomic Force Microscopy
08:41

Measuring the Mechanical Properties of Living Cells Using Atomic Force Microscopy

Published on: June 27, 2013

原子力显微镜揭示了与小鼠和人类卵细胞皮质结构相关的机械性质的差异

Rose Bulteau1,2, Lucie Barbier2, Guillaume Lamour1

  • 1LAMBE, Univ Evry, CNRS, Université Paris-Saclay, Évry-Courcouronnes, 91025, France.

Small (Weinheim an der Bergstrasse, Germany)
|March 31, 2025
PubMed
概括

卵细胞的机械性质,受动蛋白皮层厚度的影响,影响卵细胞质量. 母亲年龄影响机械和皮质结构,在人类和小鼠卵细胞发育中观察到特定物种的差异.

关键词:
在Actomyosin皮层中.原子力显微镜的原子力显微镜.生物力学 生物力学皮层张力是皮层张力.弹性模块 弹性的模块卵子细胞 卵子细胞

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Studying the Cytoskeleton01:17

Studying the Cytoskeleton

The cytoskeletal architecture can be studied using different microscopic and biochemical techniques. Electron microscopy was instrumental in discovering the cytoskeletal architecture around the 1960s, which allowed obtaining structural information at a high-resolution level. However, the sample preparation procedure often limits this ability in biological samples. Several protocols have been developed over the years to optimize sample preparation. In one of the protocols known as rotary...