[性结肠炎中营养不良的危险因素,并发症为皮肤质性结肠炎和基于拉索回归的预测模型的构建]
Lin Shen1, Cuihao Song1, Congmin Wang2
1Department of Dermatology, First Medical Center of PLA General Hospital, Beijing 100853, China.
性结肠炎的营养不良风险与疾病持续时间,活动,慢性疾病,焦虑和睡眠质量有关. 一个预测模型准确地识别了有风险的患者.
科学领域:
- 胃肠病学和皮肤病学
- 临床营养学 临床营养学
- 预测建模预测建模
背景情况:
- 性结肠炎 (UC) 和皮肤炎 (PG) 是一种慢性炎症性疾病.
- 营养不良是UC和PG同时发生的患者的一个重大问题.
- 识别营养风险因素对于及时干预至关重要.
研究的目的:
- 鉴定PG复杂的UC患者营养不良的危险因素.
- 开发和验证这个患者群体中营养风险的预测模型.
主要方法:
- 对277名UC和PG患者的回顾性分析.
- 在营养不良和正常营养群体之间比较人口,生活方式和疾病相关因素.
- 拉索回归用于风险因素选择和名ogram模型构建.
主要成果:
- 在营养不良和正常营养组之间观察到21个因素的显著差异.
- 确定了6个营养不良的主要预测因素:UC持续时间,UC活动,PG持续时间,慢性疾病数量,SAS得分和睡眠质量.
- 在临床病例中,Nomogram模型显示出高预测准确性 (AUC=0.992) 和100%准确性.
结论:
- 疾病持续时间 (UC和PG),疾病活性,并发症,焦虑和睡眠质量是营养不良的重要风险因素.
- 开发的诺莫格拉姆模型有效地预测了PG复杂的UC患者的营养不良.
- 这个模型可以帮助临床医生在早期识别和管理营养不良.
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