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大脑动脉瘤和父动脉中的血液动力学与不完全扩张的流量转换器支架

Soichiro Fujimura^1,2, Kazuya Yuzawa^2,3, Katharina Otani^4,5

¹Department of Mechanical Engineering, Tokyo University of Science, Tokyo, Japan.

International journal for numerical methods in biomedical engineering

|March 31, 2025

概括

大脑动脉瘤中流量转移支架 (FDS) 的不完全扩张可能导致不良的血液动力学变化,增加风险. 计算流体动力学揭示,不完整的支架扩张导致动脉瘤治疗的最佳条件下.

科学领域:

生物医学工程生物医学工程
医疗成像医学成像
流体动力学流体动力学

背景情况:

编织式支架,包括流量转移支架 (FDS),用于脑动脉瘤.
在部署期间不完全扩张支架 (IncompSE) 是一个潜在的并发症.
IncompSE可能导致支架的放置不良,增加并发症和动脉瘤不完全堵塞的风险.

研究的目的:

通过计算流体动力学 (CFD) 来研究与IncompSE相关的血液动力学参数.
为了比较完整支架扩张 (CompSE) 和IncompSE之间的血液动力学变化.

主要方法:

产生了三个基本的几何形状,代表一个内部动脉吸管动脉瘤.
对12个模式进行了CFD分析:预部署,CompSE和IncompSE (远距离和近距离).
计算了影响阻塞或并发症的血液动力学参数的变化率 (CR).

主要成果:

康普塞导致动脉瘤体积流量 (VF) 和最大壁切应力 (WSS) 显著下降.
IncompSE导致了更高的VF,入流喷射,,并在动脉瘤部和母动脉增加WSS.
在IncompSE病例中,静态压力和能量损失在动脉瘤内增加,与CompSE不同.

结论:

FDS的不完全支架扩张 (IncompSE) 可以诱导不利的血液动力学变化.
这些变化包括增加血液流动和动脉瘤内的高压,可能阻碍治疗的有效性.
对CFD分析对于了解IncompSE在脑动脉瘤治疗中的血液动力学影响是有价值的.

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