在智利成年人口和马普切族群中血液学参数的参考间隔
Pablo J Letelier1, Carolina A Chicahual1, Nicolas F Arroyo1
1Precision Health Research Laboratory, Departmento de Procesos Diagnósticos y Evaluación, Facultad de Ciencias de la Salud, Universidad Católica de Temuco, Temuco, Chile.
Advances in laboratory medicine
|March 31, 2025
概括
血液学参考间隔 (RI) 在智利因性别和种族而有显著差异. 这些变异对于在多民族人群中准确的临床解释至关重要,影响患者的护理.
科学领域:
- 临床实验室科学 临床实验室科学
- 血液学 血液学 血液学
- 人口健康 人口健康
背景情况:
- 参考间隔 (RI) 对于临床决策至关重要.
- 由于遗传学和环境,RI存在个体变异.
- 智利的多民族性质需要针对特定种族的RI研究.
研究的目的:
- 为智利一般人口建立血液学参考间隔.
- 为了确定专门针对马普切族群的参考间隔.
- 为了研究血液学参数的基于性别和种族的变化.
主要方法:
- 分析了356名成年人 (18-65岁) 的样本.
- 146名参与者属于马普切族群.
- 使用非参数方法 (IFCC推) 和Tukey围来检测异常值.
主要成果:
- 在血红蛋白和血小板计数方面,性别之间观察到显著差异 (p<0.05).
- 红细胞 (RBC),血红蛋白 (HGB) 和血红素 (HCT) 显示出显著的种族差异 (p<0.0001).
结论:
- 血液学RI受性别和种族的影响.
- 为了准确的临床解释,必须考虑这些变异在多民族人群中.
- 了解个体特征可以提高诊断准确度.
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