间歇性支臂疗法治疗期性非黑色素瘤皮肤癌:对器官和功能保存的影响
Ashwini Budrukkar1, Maneesh Singh1, Monali Swain1
1Department of Radiation Oncology, Tata Memorial Hospital, Homi Bhabha National Institute (HBNI), Mumbai, India.
概括
高剂量速率间歇性胸膜疗法 (HDR-ISBT) 有效治疗皮肤非黑色素瘤皮肤癌,实现了优秀的局部控制和保持器官功能,具有良好的化品效果.
科学领域:
- 在瘤学瘤学.
- 皮肤病学 皮肤病学
- 辐射瘤学 辐射瘤学
背景情况:
- 周周非黑色素瘤皮肤癌存在独特的治疗挑战.
- 间歇性支臂疗法为这些瘤提供了精确的治疗方法.
研究的目的:
- 评估为期性非黑色素瘤皮肤癌进行间歇性支架疗法的局部控制,毒性和功能/化品结果.
- 为了评估治疗后的器官和功能保存.
- 为了分析间歇性支臂疗法后的化品结果.
主要方法:
- 追溯分析了16名患有周期性皮肤癌的患者,这些患者接受了高剂量率 (HDR) 间歇性胸膜疗法 (ISBT) 使用192-Iridium.
- 从2010年12月至2022年7月期间从前性维护的数据库中收集的数据.
- 评估局部控制,生存,RTOG毒性和功能/化品结果.
主要成果:
- 所有接受绝对和辅助HDR-ISBT治疗的患者 (100%) 在平均73个月的随访后实现了局部控制.
- 器官和功能保存率分别为93.7%和81.2%.
- 在80%的患者中观察到良好的至优秀的化品结果.
结论:
- 高剂量速率间歇性支臂治疗是一种安全有效的治疗周期性非黑色素瘤皮肤癌.
- HDR-ISBT实现了优异的局部控制和生存率.
- 该技术在大多数患者中保留了器官和功能,具有良好的化品效果.
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