提供高血压护理服务的药剂师:随机对照试验的系统审查和元分析
Viktoria Gastens1, Stefano Tancredi1, Blanche Kiszio2
1Population Health Laboratory (#PopHealthLab), University of Fribourg, Fribourg, Switzerland.
Frontiers in cardiovascular medicine
|March 31, 2025
概括
药剂师的干预显著改善高血压患者的血压 (BP) 控制. 这项对95项可循环试验的分析证实,药剂师的护理是全球管理高血压的重要策略.
科学领域:
- 药理学和制药科学 药理学和制药科学
- 公共卫生和流行病学
- 心血管医学 心血管医学
背景情况:
- 涉及药剂师的社区护理模式可以增强血压 (BP) 管理.
- 高血压仍然是一个重大的全球健康挑战,需要有效的干预措施.
研究的目的:
- 系统地审查和综合有关药剂师主导干预措施改善高血压患者血压控制的有效性证据.
- 评估药剂师干预措施对缩和腹缩血压的影响.
主要方法:
- 通过对7个电子数据库的系统搜索,确定了截至2024年3月的随机对照试验 (RCT).
- 包括95个涉及31,168名参与者的RCT,并使用随机效应模型对血压变化的元分析.
- 亚组分析探讨了干预类型,设置和研究质量;偏差风险使用Cochrane风险偏差工具2进行了评估.
主要成果:
- 药剂师的干预导致了缩血压 (-5.3 mmHg) 和腹缩血压 (-2.3 mmHg) 的显著降低.
- 涉及合作,门诊设置和提供者教育/反的干预措施显示潜在的更大降低了血压.
- 对高质量的研究的分析证实了这些发现,但异质性减少.
结论:
- 药剂师护理始终改善高血压患者的血压控制,跨越各种环境和干预类型.
- 整合药剂师护理是解决全球高血压和心血管疾病负担的关键组成部分.
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