探索Prunus mahaleb提取物作为功能应用天然生物活性化合物的来源的实用性
Bayram Atasagun1, Ahmet Uysal1, Noha Fathallah2
1Department of Medical Services and Techniques Vocational School of Health Services, Selcuk University Konya Türkiye.
Food science & nutrition
|March 31, 2025
概括
普鲁努斯mahaleb树枝和叶子表现出强大的抗氧化和抗变异性质,具有显著的抗菌活性. 这种多功能植物显示出开发促进健康的药物,化品和营养品的前景.
科学领域:
- 植物化学 植物化学
- 药理学 药理学是指药理学的学科.
- 自然产品 化学 化学
背景情况:
- 普鲁努斯mahaleb因其药用价值和功能性质而闻名.
- 了解其化学成分和生物活动对于其应用至关重要.
- 包括水果,叶子和枝条在内的各种植物部分是生物活性化合物的潜在来源.
研究的目的:
- 为了确定Prunus mahaleb果实,叶子和树枝的化学成分.
- 评估P. mahaleb提取物的抗氧化剂,酶抑制,变异原/抗变异原和抗菌活性.
- 确定负责观察到的生物效应的关键代谢物.
主要方法:
- 使用甲醇和乙烯酸乙烯提取P.mahaleb部分.
- 使用DPPH,ABTS,CUPRAC,FRAP,聚和金属化试验评估抗氧化活性.
- 使用高性能液体染色学-电子喷射电离-质谱法/质谱法 (HPLC-ESI-MS/MS) 进行化学分析.
- 酶抑制试验 (AChE,BChE,铁酶,胺酶,葡萄糖酶).
- 使用艾姆斯试验进行变异性和抗变异性测试.
- 抗菌功效通过微稀释试验来确定.
主要成果:
- 树枝的甲醇提取物在多个测试中显示出卓越的抗氧化能力.
- 树枝提取物显示出最高的铁酶抑制活性.
- 在HPLC-ESI-MS/MS分析中,发现了40种代谢物,其中酸,纳灵宁和尿素占主导地位.
- 在艾姆斯试验中没有观察到任何突变性潜力.
- 枝枝和叶子提取物对框架转移和基对替代突变 (85-98%的抑制) 显示出显著的抗变异作用.
- 提取物对 Sarcina lutea,Bacillus cereus,Candida albicans 和 Staphylococcus aureus 具有广泛的抗菌活性.
结论:
- 普鲁努斯·马哈勒布 (Prunus mahaleb) 具有显著的抗氧化,抗变异和抗菌特性.
- 树枝和树叶的提取物特别丰富于生物活性化合物.
- 已识别的代谢物,如酸和宁素,有助于植物的生物活动.
- 普鲁努斯·马哈勒布 (Prunus mahaleb) 是开发促进健康产品的宝贵来源.
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