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活着的脏捐赠后的丸疼痛:来自多中心队列研究的结果
Amit X Garg1,2,3,4,5, Liane S Feldman6, Jessica M Sontrop2,3
1Victoria Hospital, London Health Sciences Centre, ON, Canada.
Canadian journal of kidney health and disease
|March 31, 2025
概括
男性脏捐赠者报告的丸疼痛明显高于非捐赠者. 这种单方面的疼痛,通常与手术的一面相同,表明与脏捐赠有联系,需要进一步研究.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 移植手术 移植手术
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 一些男性脏捐赠者在捐赠后报告丸疼痛,但由于缺乏对照组,直接归因不清楚.
- 之前的研究并没有比较捐赠者与非捐赠者之间的疼痛发生率.
研究的目的:
- 为了比较男性活体脏捐赠者与男性非捐赠者的丸疼痛发生率.
- 为了确定潜在的风险因素和特征与切术后丸疼痛相关.
主要方法:
- 一项队列研究比较了351名活着的男性脏捐赠者和126名男性非捐赠者,在基线健康特征上使用治疗权重的逆概率进行了匹配.
- 参与者在基线和基线后3年的中位数填写了关于疼痛 (丸,眼睛,手) 的问卷.
- 使用权重分析来评估两组之间的丸疼痛风险比率.
主要成果:
- 与非捐赠者 (2,3%) 相比,男性脏捐赠者丸疼痛的风险明显高 (17.6%),加权风险比率为7.8.8.
- 捐赠者的丸疼痛主要是单边的,与切除术 (90.2%) 相同的一面.
- 腹腔镜手术与丸疼痛的发病率较高,与捐赠者的开放手术相比.
结论:
- 与切除术相同的一侧单侧丸疼痛是活体脏捐献的潜在并发症.
- 这些发现表明,脏捐赠,特别是腹腔镜切除术,与丸疼痛的发展之间存在联系.
- 需要进一步的研究,以了解捐赠后丸疼痛的机制和管理.
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