目前的Candida感染流行病学
1Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA.
Clinical microbiology newsletter
|March 31, 2025
概括
常见的医疗保健感染 - - 候群病 - - 显示了物种流行率的变化,Candida albicans的数量正在下降,而C. glabrata等非白虫物种的数量在增加. 抗真菌耐药性仍然是一个问题,特别是在C. glabrata.
科学领域:
- 传染性疾病 传染性疾病
- 菌类学 菌类学是指菌类学.
- 医疗卫生流行病学 医疗卫生流行病学
背景情况:
- кандидемия和 кандидоз是导致医疗保健相关感染的主要原因,有助于显著的患者发病率和死亡率.
- 虽然*Candida albicans*在历史上占主导地位,但其在美国候选病例中的比例已经下降到50%以下.
研究的目的:
- 分析物种分布的演变趋势和候选菌病的抗真菌易感性模式.
- 为了突出非*Candida albicans*物种,如*C. glabrata*在候选症病例中越来越普遍.
主要方法:
- 对候选病和候选症发病率的流行病学数据的审查.
- 对物种识别和抗真菌敏感性测试结果的分析.
- 对美国和全球趋势的比较评估.
主要成果:
- *Candida albicans*不再是导致美国白病的多数物种,现在占病例的不到50%.
- *Candida glabrata*越来越普遍,占美国病例的近30%,与其他非*albicans*物种一起.
- 在全球范围内存在主要物种的区域差异; 美国的儿科候选血病率在没有明确原因的情况下正在下降.
- 抗真菌耐药性总体上仍然很低,但存在关于素和*C. glabrata*多药耐药性的担忧.
结论:
- 候群病的风景是动态的,具有显著的变化在致病物种和关于抗真菌耐药性的持续担忧.
- 持续监测候群病趋势,包括物种流行和耐药性模式,对于有效的患者管理和公共卫生战略至关重要.
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