青少年皮肤肌炎病例呈现与逆哥特龙斑块:一个病例报告
Renad AlKanaan1, Iman I Nazer2, Monira AlNasser3
1College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Case reports in dermatology
|March 31, 2025
概括
反向哥特朗斑块是青少年皮肤肌炎 (JDM) 的罕见症状. 这一案例凸显了在患有JDM的儿童中检查这些斑块是否存在间歇性肺病 (ILD) 的重要性.
科学领域:
- 儿科风湿病学 儿科风湿病学
- 皮肤病学 皮肤病学
- 罕见疾病 罕见疾病
背景情况:
- 反向哥特朗斑块是一种不常见的皮肤肌炎 (DM) 呈现.
- 有限的研究存在于青少年皮肤肌炎 (JDM) 中的逆哥特朗斑块.
- 反向Gottron的斑块与DM中的间歇性肺病 (ILD) 有关.
研究的目的:
- 报告一个JDM病例,呈现出反向Gottron的斑块.
- 为了强调反向哥特朗斑块和JDM中的ILD之间的关联.
- 为了突出沙特阿拉伯首次报告的JDM与逆Gottron斑块的病例.
主要方法:
- 一个5岁的女孩出现了日光标志,哥特朗的斑块,反向哥特朗的斑块,以及近端肌肉软弱.
- 诊断工作包括实验室调查 (肌肉酶,肌炎特异性抗体,肝功能测试),HRCT胸部和全身MRI.
- 治疗包括静脉注射甲基普雷迪尼索隆和局部皮质类固醇.
主要成果:
- 患者表现出JDM的特征性皮肤和肌肉参与.
- 实验室检测显示肌肉酶升高,肌肉炎特异性抗体呈阳性.
- 全身MRI证实了泛性肌炎和皮下,导致了JDM诊断. 胸部HRCT显示没有ILD.
结论:
- 反向哥特朗斑块是JDM中罕见但重要的发现.
- 患有JDM和逆Gottron斑块的患者需要对ILD进行调查.
- 这个案例代表了沙特阿拉伯首次报告的JDM与逆Gottron的斑块的实例.
相关概念视频
Papillary Dermis
Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Skin Diseases and Disorders
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Reticular Dermis
The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Myocarditis II: Clinical Features and Diagnostic Tests
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
Acne Infection
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...


