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Updated: May 17, 2025

A Fluorogenic Peptide Cleavage Assay to Screen for Proteolytic Activity: Applications for coronavirus spike protein activation
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切割与未切割:福林切割如何重塑SARS-CoV-2尖峰的形态格局

Natesan Mani1, Raghavendran Suresh1, Srirupa Chakraborty1

  • 1Department of Chemical Engineering, Northeastern University, Boston, MA 02115; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115.

bioRxiv : the preprint server for biology
|March 31, 2025
PubMed
概括

SARS-CoV-2尖端蛋白的furin裂变通过改变蛋白质动态和灵活性来增强受体结合. 了解这种分裂对于有效的疫苗和治疗开发至关重要.

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