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Updated: May 21, 2025

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沉默KRIT1部分扭转了干扰流动对内皮细胞转录组的影响

Amelia Meecham1, Sara McCurdy1, Eduardo Frias-Anaya1

  • 1Department of Medicine, University of California, San Diego, La Jolla, CA 92093.

bioRxiv : the preprint server for biology
|March 31, 2025
PubMed
概括

静止内皮细胞中的KRIT1可以在血液流动受损的情况下恢复保护性KLF2/KLF4基因表达. 这一发现表明,向CCM复合体可以通过增强内皮细胞的弹性来预防动脉样硬化.

关键词:
脑内皮质 (Endothelium) 是一个内皮.动脉样硬化 动脉样硬化它们是内皮细胞.振荡式剪切应力压力 振荡式剪切应力脉动式剪切应力压力血管保护 血管保护

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