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Updated: May 17, 2025

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针对向蛋白质降解的异构功能蛋白质仿真聚合物

Max M Wang, Mihai I Truica, Brayley S Gattis

    bioRxiv : the preprint server for biology
    |March 31, 2025
    PubMed
    概括

    一种新的聚合物化学方法,混合降解聚合物 (HYDRAC),使MYC和KRAS等具有挑战性的疾病点的向蛋白降解 (TPD) 成为可能,在体内显示出显著的瘤抑制.

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