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在糖尿病患者中HbA1c水平和牙周细菌负荷之间的相关性固定保留器

Mihaela Mariș¹, Sorana Maria Bucur², Marius Mariș³

¹PhD student, Doctoral School, Faculty of Medicine and Pharmacy, "Dunarea de Jos" University of Galati, Romania.

Current health sciences journal

|March 31, 2025

概括

固定牙科支器增加了糖尿病患者的细菌负载. 良好的血糖控制和口腔卫生显著降低了这种风险,改善了牙周健康.

科学领域:

牙周病学牙周病学
内分泌学在内分泌学.
微生物学微生物学

背景情况:

固定的正牙保持器可以导致生物膜积累.
这给2型糖尿病患者带来了牙周风险的增加.

研究的目的:

为了检查糖化血红蛋白 (HbA1c) 水平和细菌负载之间的关系.
评估口腔卫生干预对固定保持器的糖尿病患者细菌负载的影响.

主要方法:

40名糖尿病患者 (HbA1c:6.5%-9%) 被分为两个年龄组.
使用micro-IDent® PCR分析了牙周样本.
皮尔森的相关性和线性回归分析了HbA1c和细菌负载之间的关联.

主要成果:

干预前的细菌负载明显高于干预后的负载 (p≤0.05).
HbA1c与干预前的细菌负载有很强的正相关性 (r=0.78,p=0.002),干预后下降 (r=0.42,p=0.08).
每增加1%的HbA1c与细菌负载预干预显著增加相关 (R2=0.61).

结论:

固定保持剂促进细菌殖民,加剧糖尿病患者的牙周炎症.
有效的血糖控制对于减轻细菌负载至关重要.
定期的口腔卫生干预对于预防牙周并发症在这个患者群体中至关重要.

关键词:

固定式保持器固定式保持器这就是HbA1c.的细菌负载.2 型糖尿病 2 型糖尿病

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