治疗儿童甲状腺结节:一个单一中心的经验
Malika El Omri1, Oumaima Gabsi1, Mouna Bellakhdher1
1Department of Ear, Nose, Throat and Head and Neck Surgery, Farhat Hached University Hospital, University of Sousse, Sousse, 4000, Tunisia.
Iranian journal of otorhinolaryngology
|March 31, 2025
概括
儿童甲状腺结节很少见,但由于恶性瘤风险,需要立即评估. 这项研究分析了29例儿科病例,详细介绍了结节的特征和有效管理的手术结果.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 手术瘤学手术瘤学
背景情况:
- 甲状腺结节在儿童中并不常见,与成年人不同.
- 由于儿科病例中恶性瘤的可能性较高,早期诊断和管理至关重要.
- 这项研究的重点是描述儿科甲状腺结节以指导治疗策略.
研究的目的:
- 描述儿童患者甲状腺结节的临床和病理特征.
- 评估患有甲状腺结节的儿童的手术管理和结果.
- 为儿童甲状腺结节的诊断和治疗方法提供信息.
主要方法:
- 对29名儿童患者的回顾性分析,这些患者在2000年至2022年期间接受了甲状腺结节手术.
- 对患者人口统计,出现症状,手术,组织学发现和随访数据的审查.
- 从耳鼻科的外科记录中收集的数据.
主要成果:
- 该研究包括29名儿童 (平均年龄14.4岁,主要是女性).
- 前宫胀是最常见的症状 (82.7%).
- 在13.8%的病例中诊断出乳头癌;所有患者都经历了手术后的良好结果.
结论:
- 儿童甲状腺结节需要彻底评估,包括超声波和细胞学,以评估恶性瘤风险.
- 根据这些评估进行适当的手术管理对于有利的结果至关重要.
- 了解结节的特征有助于规划儿童甲状腺结节的有效治疗策略.
更多相关视频
相关概念视频
The Thyroid Gland
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Synthesis and Regulation of Thyroid Hormones
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The iodine is then...
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The iodine is then...
Goiter
Goiter refers to an abnormal enlargement of the thyroid gland that may appear as a diffuse goiter (uniform enlargement) or nodular (single or multiple nodules). Functionally, it is classified as nontoxic (normal/low hormone levels) or toxic (excess hormone production).PathophysiologyDiffuse thyroid enlargement typically results from prolonged stimulation by thyroid-stimulating hormone (TSH) or TSH-like agents, commonly seen in hypothyroidism or iodine deficiency. In contrast, in hyperthyroid...


