在瑞典,对无控高血压的射频脏损的成本效益分析
T Kahan1,2, M L Johansen3, A M Ryschon4
1Karolinska Institute, Stockholm, Sweden.
Blood pressure
|March 31, 2025
概括
射频损伤 (RF RDN) 是瑞典无控制高血压的经济有效治疗方法. 这种疗法提供了显著的长期健康益处和改善生活质量,使其成为患者的有价值选择.
科学领域:
- 心血管医学 心血管医学
- 卫生经济学 卫生经济学
- 干预性心脏病学 干预性心脏病学
背景情况:
- 失控的高血压带来了严重的健康风险和经济负担.
- 射频损伤 (RF RDN) 是一种新兴的以导管为基础的治疗方法,用于治疗耐性高血压.
- 评估新型治疗方法的成本效益对于医疗保健系统的可持续性至关重要.
研究的目的:
- 评估RF RDN与瑞典无控高血压的标准护理 (SoC) 相比的成本效益.
- 预测临床结果,成本和经质量调整的寿命年 (QALYs) 在10年和终身时间范围内.
- 为了确定增量成本效益比率 (ICER) 与支付意愿值相比.
主要方法:
- 使用决策分析的马尔科夫模型来模拟健康状态和转变.
- 来自SPYRAL HTN-ON MED试验的临床数据为该模型的治疗效果估计提供了信息 (-4.9 mmHg SBP减少).
- 该分析从瑞典医疗保健支付者的角度进行,包括敏感性分析.
主要成果:
- 在10年内,RF RDN表明中风 (0.80),心肌梗塞 (0.88),心力衰竭 (0.72) 和心血管死亡 (0.86) 的风险降低.
- 终身预测显示,使用RF RDN的增量成本为63,136瑞典克朗,QALY收益为0.45.
- 由此产生的ICER为每个获得的QALY139,280瑞典克朗,这表明了成本效益.
结论:
- 预计RF RDN将成为瑞典不受控制和耐药高血压的经济有效治疗方法.
- 该模型的发现支持采用基于当前临床证据的RF RDN.
- 这一分析为医疗保健决策提供了有价值的经济见解,涉及到RF RDN.
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