利用迷幻药来提高幸福感:一个系统的审查
Samuel Thomson1, Nikos Thomacos1
1School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology (RMIT), Melbourne, Australia.
Journal of psychoactive drugs
|March 31, 2025
概括
迷幻药物,包括psilocybin和LSD,可以通过改善积极的情绪,参与,关系,意义和成就来提高健康个体的幸福感. 这一系统性审查表明,应该转向认识到它们在治疗应用之外促进人类繁荣的潜力.
科学领域:
- 心理药理学和积极心理学
背景情况:
- 传统上,迷幻药物的研究主要集中在治疗精神疾病的治疗应用上.
- 幸福的PERMA理论为评估健康人群的繁荣提供了一个框架.
研究的目的:
- 系统地审查现有的关于迷幻物质对健康个体福祉影响的文献.
- 应用PERMA幸福理论 (积极的情绪,参与,关系,意义,成就) 来评估这些影响.
主要方法:
- 来自五个学术数据库的19项研究 (1994-2024) 的系统审查.
- 纳入标准:受控或自然主义的实验设计,结果测量在消费后≥7天.
- 研究涉及949名参与者中的5-MeO-DMT,亚华斯卡,LSD和 псилоцибин.
主要成果:
- 迷幻药的消费一直与PERMA模型所有五个要素的持久改善有关.
- 在讨论不良事件的六项研究中没有报告严重的不良影响.
- 积极的结果包括增强的积极情绪,参与,关系,意义和成就.
结论:
- 迷幻药在健康个体中显示出增强幸福感和促进人类繁荣的潜力.
- 这些发现表明,从以疾病为重点的方法转向认识到迷幻药的更广泛益处的范式转变.
- 建议对更大规模的纵向随机对照试验进行进一步研究,以验证这些发现并全面评估幸福感.
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